A-131 Measuring the Effect of CPT-3 Administration on Regional Cerebral Blood Flow with Single-Photon Emission Computed Tomography (SPECT) in ADHD

Abstract Objective: The aim of this study is to investigate the effect administration Conners Continuous Performance Test (CPT-3) on cerebral blood flow (CBF) in children with ADHD. Methods: data for was derived from a large - database. Participants ADHD group (n = 1853, Mage 12.01) were similar those healthy control 38, 11.70). All participants assessed levels before and after CPT-3 administration. Results: Multiple 2-by-2 ANOVAs repeated measures conducted sphericity assumed. overall CBF significant right cingulate left sides frontal lobe occipital, parietal lobe, subcortical region. Post hoc analysis Bonferroni adjustment revealed that there statistically increase baseline following both groups. interaction between diagnosis not significant. Conclusions: individuals had higher CPT-3. Without an interaction, we can infer does change levels. This counterintuitive considering test sustained attention, common challenge These findings need be replicated.